Oh I got one! I had surgery about 2 years ago on my lower back, and the stitches were still fresh. The pain meds they gave me had just run out, and my mother-in-law had some oxycontins, so she gave me those until I could get to the pharmacy the next day. I took one of them, not knowing that your body can't tell the difference between that and heroin! Turns out, the first time most people do heroin, they vomit uncontrollably. Couple that with the fact that they had me taking laxitives because the pain pills that they originally had me on caused constipation, and you have one not-so-fun night. I took the oxycontin at around 10pm, and at midnight, I couldn't sleep. Apparently it's an "upper" and not a "downer." At around 2am, my stomach was in knots. It hurt so badly that I could do nothing but writhe in bed and moan. It hurt to try to get up because of the abdominal pain as well as the stitches. Then all of a sudden, I had the urge! The laxitives were definately kicking in, so I ran to the toilet. When I got there, my freakin anus exploded! lol... It was bad... very bad. On top of that, the vomiting started. Refusing to place my head where a massive biohazard had just been released, I flushed the toilet while vomiting all over the floor. Very, very bad. Every time my stomach would wrench, it would stretch the stitches apart. I ended up having to go back to the hospital due to blood loss (the entire bathroom floor was flooded with vomit and blood) and get my 27 stitches replaced.